1. Install Node.JS (Again)
This time the latest version of Node.JS, and it must be in C:\node or C:\Program Files\nodejs.

1. Install URL Rewrite and iisnode
Download URL Rewite here...
Download iisnode here...

3. Installing Additional Packages for the Web Application
Using cmd.exe as Administrator, navigate to the Web application directory within wwwroot, and enter the 'npm install package' command.

References